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How the human can breath underwater just like fish... Liquid Ventilation

In PLV (mechanical ventilation), oxygen - carrying fluids - is dripped through the lungs into the lungs of the patient. In this article I will describe how PL V is used today and how patients who receive it can be cared for. The currently preferred liquids are liquids with oxygen and carbon dioxide bearing properties (e.g. liquid oxygen, liquid carbon monoxide). Perflubron helps to open collapsed alveoli, increase gas exchange and improve lung conformity so that the ventilator can operate at the same level it reaches. This improved conformity allows ventilation with increased tidal volume, resulting in increased gas exchange and PFC fluids in the lungs, which can contribute to improved ventilation and mismatch of the perfusion. ...
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How the human can breath underwater just like fish... Liquid Ventilation


Liquid Assisted Ventilation, From Experimental Use to Intensive ...

In PLV (mechanical ventilation), oxygen - carrying fluids - is dripped through the lungs into the lungs of the patient. In this article I will describe how PL V is used today and how patients who receive it can be cared for. The currently preferred liquids are liquids with oxygen and carbon dioxide bearing properties (e.g. liquid oxygen, liquid carbon monoxide).
Perflubron helps to open collapsed alveoli, increase gas exchange and improve lung conformity so that the ventilator can operate at the same level it reaches. This improved conformity allows ventilation with increased tidal volume, resulting in increased gas exchange and PFC fluids in the lungs, which can contribute to improved ventilation and mismatch of the perfusion.
Despite the overall sustainable improvement in gas exchange, the transition from liquid to gas ventilation is straightforward due to the high cost of the LPG ventilation system and the limited availability of LPG on the market.
We now understand the mechanisms for improving circulatory disturbances in PLV settings for respiratory arrest. The hope is that the fluid will help to flood and fill parts of the lungs with debris, remove dirt and open more alveoli, thereby improving lung function. Patients can be ventilated with conventional ventilators, where the lung is filled with fluid and this dirt fills the part of the lung.
A significant improvement in oxygen supply and pulmonary mechanics was demonstrated in oleic acid - a lung injury in patients with acute lung injuries with pulmonary edema.
The aerosol apparatus is crucial for the effectiveness of PFC aerosolsization, as aerosoling of pf5080 and less purified FC77 has proved ineffective in various aerosol apparatus used in rabbits with low surfactant content. A gravitational system was used to divert the P FC from the lungs into an overhead reservoir, siphon pressure was used to cause runoff and discharge, and gas exchange was supported by perfluorocarbons. This technique is used for LV, but not for other lung diseases such as pulmonary edema or pulmonary hypertension.
Some studies have also used silicone oil as an alternative to PFCs, but this is really toxic to mammals as it inhales normal air again. TLV cannot be used in humans because the necessary equipment is not available everywhere and also because of the high cost of the equipment.
Once the fetus is born, chemicals known as surfactants help prevent the collapse of the lungs, and their lungs are filled with amniotic fluid during normal development. However, babies born prematurely have not yet developed enough lungs to prevent folding, and when they are suddenly exposed to gases in the atmosphere, they find it difficult to breathe. Several infants suffering from severe respiratory problems were given full fluid ventilation, with the lungs completely filled with PFC fluid and the lungs filled to their remaining functional capacity. They showed remarkable physiological improvements, including lung conformity and gas exchange.
High pressures of nitrogen and helium occur without the use of non-liquids, and therefore liquid breathing would reduce or eliminate the need for slow decompression. In addition, the pressure in a diver's lungs could absorb pressure changes from the surrounding water without the need for an enormous gas or partial pressure load when the lungs are filled with gases. Liquid breathing would not lead to a loss of lung function, but to an increase in lung capacity through a reduction in gas pressure.
The first thought that comes to mind when most people hear the word "fluid-filled lungs" is obvious: drowning. The use of fluid breathing during diving must include complete fluid ventilation, as seen above. PFCs have a high oxygen solubility, which means that the liquid can saturate the oxygen in the lungs with enough oxygen to continue breathing until the lungs are completely filled with fluid.
In fact, PFC fluids can actually help increase oxygen absorption by removing mucus blockages, and have the added side effect of exhibiting anti-inflammatory properties. This is one of the biggest challenges when administering P FC drugs: most drugs supplied in liquid form must be soluble in water to obtain an aqueous solution. Liquid fans use a combination of tidal breathing generated by the PPCs and the fluid itself. For the lungs to be filled with PCCs, they need to have a good understanding of how they interact with other fluids and how their solubility changes.
In order to carry out ventilation, optimum CO2 release must be achieved by using the PPCs and the liquid as well as the correct balance of oxygen and CO 2.
Unfortunately, the development of special ventilators for TLV has been challenging, and the administration of poorly controlled levels of PFC has led to a significant increase in the use of PPCs in patients with respiratory failure. One of the advantages of TLV is that the exudate can be flushed into the respiratory tract in case of respiratory diseases. As PPC has a very low surface tension and improves lung conformity, it is attractive as a solution to the problem of lung failure in patients with pulmonary embolism.

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